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#Preregistration supports #OpenScience, but is uncommon in animal research. This Meta-Research study reveals that despite known benefits, perceived bureaucracy, time costs and inflexibility hinder adoption.
@swissrn
https://plos.io/4pL0tXq
4 views
#Aging tissue gradually loses its cellular diversity as stem cells run out. Tzu-Chiao Lu & Hongjie Li explore a new @PLOSBiology study showing that early patterns in intestinal #StemCells predict which lineages will dominate in late life in flies.
Research Article https://plos.io/3SsQFVs
Primer https://plos.io/4wVkXPp
4 views
Toxin-antidote systems are selfish genetic elements found in several eukaryotic organisms. This study by Liu and Zheng describes an ancient such system in C. elegans; the maternal toxin induces a rod-like larval arrest phenotype in progeny that do not carry the antidote.
#genetics #evolution
https://plos.io/4fBW4kY
3 views
Nearly half of Swiss animal researchers have not heard of #preregistration. Pasquale Pellegrini & Ulf Toelch explore a new @PLOSBiology study mapping attitudes, barriers and misconceptions, and identifying what's needed to change minds.
Research article https://plos.io/4pL0tXq
Primer https://plos.io/44WMc08
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🔥 Top post: #Preregistration supports #OpenScience, but is uncommon in anima · 6 likes + reposts
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🔥 Top post
#Preregistration supports #OpenScience, but is uncommon in animal research. This Meta-Research study reveals that despite known benefits, perceived bureaucracy, time costs and inflexibility hinder adoption.
@swissrn
https://plos.io/4pL0tXq
Nearly half of Swiss animal researchers have not heard of #preregistration. Pasquale Pellegrini & Ulf Toelch explore a new @PLOSBiology study mapping attitudes, barriers and misconceptions, and identifying what's needed to change minds.
R…
The glucose-6-phosphate transporter mediates G6P translocation into the endoplasmic reticulum. Qi, Shen & Hattori explore two @PLOSBiology.org #structure studies providing new mechanistic insights into a crucial process.
Article 1 https://…
The human G6P transporter (SLC37A4) moves glucose-6-phosphate into the endoplasmic reticulum, supporting blood glucose stability and metabolism. This study solves the #structure of SLC37A4 in 3 conformations, providing insights substrate r…
Structural #bioinformatics aims to answer biological questions by considering biomolecular #structures at scale. This Perspective by @jgreener64 argues that now that we have accurate predictions, we need to ask what we can learn from them…
#Development requires precise temporal coordination of cellular programs. This study by Francisco Javier Romero-Expósito, María Olmedo & co reveals how reduced insulin signaling in C. elegans slows down cell division to realign development…
Reproductive organs are under strong selective pressure during #evolution. In this Primer, Mugal and Sémon explore a new @PLOSBiology study showing that Drosophila testis cells exhibit rapid change, while ovarian cells are more conserved.…
Seminiferous tubules of the testes play an important role in #sperm production. This study shows that all cell types in the mouse seminiferous epithelium display unique calcium signaling patterns that are under endocrine control.
https://p…
How do #learning processes related to reward exploitation and exploration interact with one another in the brain? This study uses behavior, neuroimaging, pharmacology, and modeling to reveal shared learning mechanisms, connecting with indi…
#Aging tissue gradually loses its cellular diversity as stem cells run out. Tzu-Chiao Lu & Hongjie Li explore a new @PLOSBiology study showing that early patterns in intestinal #StemCells predict which lineages will dominate in late life …
Toxin-antidote systems are selfish genetic elements found in several eukaryotic organisms. This study by Liu and Zheng describes an ancient such system in C. elegans; the maternal toxin induces a rod-like larval arrest phenotype in progeny…
Unprecedented amounts of biological data are available, but most is underutilized. This Perspective by Ghaderi, Ruggles, Maimon & co argues that #AI -driven reanalysis will drive the next era of discovery in #biology, but validation and st…
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